http://type2diabetestreatment.net/diabetes-type-2/study-points-to-seriousness-of-hypoglycemia-in-type-2-diabetes/
Endocrinology Advisor reported on a recent study which showed that most patients with diabetes requiring a visit to the hospital for a severe low blood sugar had type 2 diabetes.
These results were shared at the 26th American Association of Clinical Endocrinologists (AACE) Annual Scientific Sessions & Clinical Congress in Austin, Texas.
Researchers in Sarojini Naidu Medical College in Agra, India saw how there was little data on these type 2 diabetes patients who ended up in the hospital with severe hypoglycemia and sought to look into what risk factors and “associated clinical characteristics” these patients presented.
Is Low Blood Sugar Dangerous in Type 2 Diabetes?
In the prospective study, researchers studied a sample of 50 patients with diabetes who had showed up at the hospital with “altered consciousness” and blood sugar at or below 70 mg/dL (3.9 mmol/L). Those with “malignancies, acute cerebrovascular events, symptomatic congestive heart failure, or an estimated glomerular filtration rate (eGFR) <10 were excluded from the study.”
Of the 50 patients, 2 died in the hospital and 2 others died within 90 days, all four had type 2 diabetes. Of all the low blood sugar episodes, 82 percent of the cases involved type 2 diabetes patients.
Who May Be More at Risk for Severe Low Blood Sugar?
Cases of severe low blood sugar are a serious issue in some patients with type 2 diabetes. What are the characteristics and risk factors of these patients?
According to the study authors, 17 patients were taking either a sulfonylurea or insulin, 19 were on 2 medications and 14 were on 3 or more medications. Mostly prescribed was a sulfonylurea, of which 32 of the patients were on.
Based on the limited study results, the cases of severe low blood sugar in those with type 2 diabetes were strongly tied to use of the combination of a sulfonylurea and metformin (78%).
The average age for those with type 2 diabetes was 66 and the average age in those with type 1 diabetes was 32. The average plasma glucose of all the participants was 37 mg/dL and the average HbA1c was 8.6 percent.
Of the 50 patients who went to the hospital for low blood sugar, 14 had previously been admitted for the same reason.
The researchers stated that “More than half of patients were illiterate or uninformed about hypoglycemia,” Many of the patients may have had some impaired kidney function which might have been a “potential contributing factor”.
Endocrinology Advisor reported that the researchers concluded, “severe hypoglycemia is an important risk factor for [a] short-term increase in all-cause mortality, particularly in [patients with] type 2 diabetes,”
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