Never give in except to convictions of honor and good sense.

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Research links aortic stiffness to A1C in patients without diabetes A1C and homeostatic model assessment of insulin resistance were associated with the progression of aortic stiffness, measured by carotid femoral pulse wave velocity, among individuals without diabetes after adjusting for cardiovascular risk factors and physiological confounders, according to a study in Diabetes Care. UK researchers used a cohort of 4,386 individuals without diabetes and found a weakened correlation between aortic stiffness and HOMA-IR, but not with A1C, after additional adjustment for body mass index. Physician"s Briefing/HealthDay News (2/7) Lower A1C levels seen in people with sickle cell trait, study finds A study in the Journal of the American Medical Association showed that African Americans with a sickle cell trait had A1C levels of 5.72%, compared with 6.01% among those without SCT. The findings, based on 4,620 African Americans, revealed that low A1C levels were associated with significantly lower rates of prediabetes and diabetes when participants were diagnosed with A1C criteria. MedPage Today (free registration) (2/7) Wound-healing gel tested on diabetic cells University of Toronto researchers developed a peptide-hydrogel biomaterial that closed nonhealing wounds 200% faster than using no treatment and 60% faster than treatment with a common collagen-based product. The study in the Proceedings of the National Academy of Sciences tested the biomaterial using keratinocytes from healthy human cells and those derived from older diabetic patients. McKnight"s Long-Term Care News online (2/5)

AHA advises against late-night eating An American Heart Association statement in the journal Circulation suggests that cardiovascular disease risk can be reduced by consuming the bulk of meals and snacks during the day and avoiding the consumption of calories late in the evening or at night. Animal studies have shown that receiving food while organs are in an inactive phase resets internal clocks in a way that can change nutrient metabolism and cause weight gain, insulin resistance and inflammation. Miami Herald (tiered subscription model) (2/6) Study assesses pediatric weight-management for Latino children Researchers said weight-management care benchmarks, such as weight management referrals and recommended lab testing, often are not met for overweight Latino children. The study in the journal Global Pediatric Health found benchmarks were not communicated or documented in 42% of primary care visits for overweight or obese Latino children ages 6 to 12. United Press International (2/6) Study shows how exercise may benefit heart tissue Research published in Experimental Physiology found 30 minutes on a treadmill may increase expression of genes that repair damaged DNA, helping to remodel heart tissues. University of Maryland researcher Stephen Roth said the process may contribute to the cardiovascular protection that exercise provides. Business Standard (India)/Asian News International (2/7)

Study: Hospice less likely for severely obese patients A study in the Annals of Internal Medicine found about 35% of almost 5,700 Medicare beneficiaries who died from 1998 to 2012 received hospice care, but just 23% of those deemed severely obese received hospice services. Data showed severely obese patients in hospice care received services for four fewer days and fewer died at home, compared with people with a BMI of 20. HealthDay News (2/6) Physicians may need to ramp up health IT for MACRA, experts say Physician practices may need to increase adoption of health care IT to successfully transition to working within the Medicare Access and CHIP Reauthorization Act, IT experts say. Lawrence Kocot at KPMG said practices that have transitioned to or are moving toward certified electronic health record technologies will be better able to perform in MACRA"s Merit-based Incentive Payment System. Health Data Management (2/6)

Eligible health care professionals have until March 13 to submit 2016 EHR data Eligible professionals, qualified clinical data registries, Physician Quality Reporting System group practices and qualified EHR data submission vendors may submit 2016 Physician Quality Reporting System EHR data until March 13, the CMS announced. Health care professionals will receive lower payments on Medicare Part B Physician Fee Schedule services in 2018 if they fail to meet the requirements. BeckersHospitalReview.com (2/6) OMB offers guidance on Trump"s "one in, 2 out" order (Pool/Getty Images) A question-and-answer guidance has been released by the Office of Management and Budget to help the FDA and other federal agencies evaluate how the "one in, two out" executive order will affect their rulemaking and issuance of guidance. The OMB noted that the executive order gives agencies that deal with public safety some room to waive the requirement, but that overall, "any existing regulatory action that imposes costs and the repeal or revision of which will produce verifiable savings may qualify," including the FDA"s 24 final rules and one proposed rule issued last year. Regulatory Focus (2/6)

64th Advanced Postgraduate Course -- early bird registration rates extended through the meeting The Course will be held in Washington, D.C., on Feb. 17-19. There"s still time to attend live and in-person and earn up to 14.25 CE hours. The Course will cover the latest clinical research translated into evidence-based treatment strategies to improve outcomes in your patients with diabetes. Discuss clinical cases with our world-renowned faculty and take home practical patient management tools that you can begin using immediately in your practice. Learn more and register. Learn more about DiabetesPro: DiabetesPro Home | Professional Education | Journals Research Grants | Recognition Programs | Membership

Press Releases ProtoKinetix Updates Testing Progress on Neuronal Retinal Cells in Living Tissue for the Treatment of Macular Degeneration Post a Press Release

Never give in except to convictions of honor and good sense. Winston Churchill, statesman and prime minister

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